Tamsulosin hydrochloride ( LY253351; YM-12617-1 )

产品货号. M10281 CAS No. 106463-17-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

Tamsulosin hydrochloride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Tamsulosin is a selective antagonist at alpha-1A and alpha-1B-adrenoceptors in the prostate, prostatic capsule, prostatic urethra, and bladder neck.
产品描述

Tamsulosin is a selective antagonist at alpha-1A and alpha-1B-adrenoceptors in the prostate, prostatic capsule, prostatic urethra, and bladder neck. At least three discrete alpha1-adrenoceptor subtypes have been identified: alpha-1A, alpha-1B and alpha-1D; their distribution differs between human organs and tissue. Approximately 70% of the alpha1-receptors in human prostate are of the alpha-1A subtype. Blockage of these receptors causes relaxation of smooth muscles in the bladder neck and prostate.
同义词

LY253351; YM-12617-1
通路

Endocrinology/Hormones
靶点

Adrenergic Receptor
受体

α1A-adrenergic receptor; α1B-adrenergic receptor; α1D-adrenergic receptor
研究领域

Neurological Disease
适应症

——

CAS Number

106463-17-6
分子量

444.97
分子式

C20H29ClN2O5S
纯度

>98%(HPLC)
溶解度

Water: 215.9 mg/L
SMILES

O=S(C1=CC=C(C[C@H](NCCOC2=CC=CC=C2OCC)C)C=C1)(N)=O.[H]Cl
化学全称

5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-benzenesulfonamide hydrochloride

1.Abrams P, et al. Br J Urol. 1997 Oct; 80(4):587-96.

计算器

产品手册

关联产品

Salbutamol

Salbutamol is a short-acting β2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD).
Nadolol

A non-selective beta-adrenergic antagonist with a long half-life, used in cardiovascular disease to treat arrhythmias, angina pectoris, and hypertension.
Betaxolol hydrochlor...

Betaxolol Hydrochloride is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.